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Karnataka Health Promotion Trust (KHPT) works closely with the University of Manitoba, Canada and the Karnataka State AIDS Prevention Society to empower communities in Karnataka, to improve their health, reduce the incidence and burden of HIV and AIDS, and assert their rights and dignity.

Some of their projects are as follows:

• Sukshema Project: Sukshema Project is the Maternal & Child Health Program, implemented by KHPT in partnership with the National Rural Health Mission Program of the Government of Karnataka. It is funded by the Bill & Melinda Gates Foundation and supports the state of Karnataka and India to improve maternal, new born and child health outcomes by improving availability, accessibility, utilization and coverage of critical MNCH interventions for rural populations of eight priority districts in northern Karnataka.
• STRIVE: STRIVE is a research consortium, investigating the social norms and inequalities that drive HIV. A collaboration between six partners, STRIVE is funded by the UKaid/ Department for International Development and led by the London School of Hygiene and Tropical Medicine (LSHTM). KHPT as part of STRIVE is implementing and evaluating two programmes - Samata and Samvedana Plus, focusing on how structural factors, such as gender inequality and violence drive the HIV epidemic.
• India Learning Network (ILN): This project is implemented in partnership with Family Health International (FHI) 360 and the University of Manitoba. It is funded by the Bill & Melinda Gates Foundation. The project aims to influence global HIV prevention practices by widely disseminating the approaches and learning that evolved from scaled HIV interventions in India. The project works to enhance the capacities of the programmers, policy makers and implementers from countries in Asia and Africa.
• Samvedana: It is funded by the United Nations Trust Fund and implemented in partnership with sixteen Community Based Organizations (CBOs). The project is implemented in collaboration with the National Law School of India University, Karnataka State AIDS Prevention Society, Karnataka Judicial Academy, Centre for Advocacy and Research and the National Institute of Mental Health and Neuro Sciences. The project works towards addressing violence against women in sex work in 30 districts of Karnataka.